Gestational Diabetes Mellitus and Correlation with Serum Total Cholesterol Levels

  • ZOHRA KHANUM, AMNA KHANUM, SALMAN JAVED
Keywords: Gestational diabetes mellitus, Term Pregnancy, Serum total cholesterol

Abstract

Objective: The objective of this study was determine the frequency of GDM in females presenting in a tertiary care hospital and to compare total cholesterol level in females presented with or without gestational diabetes at term.

Material and Methods: This Cross Sectional Study was carried in Unit 3, Department of Obstetrics and Gynecology, Sir Ganga Ram Hospital Lahore. Study durtion was six months from January, 2017 to June 2017. A total of 320 females, fulfilling the inclusion and exclusion criteria were selected in this study from OPD Department. Their demographic details including name, age, BMI, gestational age and parity was also be noted. Females were assessed for presence or absence of GDM. Fasting blood samples were drawn by using 5cc BD syringe. All samples were sent to laboratory of the hospital and reports were assessed. Total cholesterol level was noted on predesigned Performa.

Results: A total of 320 cases fulfilling the inclusion/exclusion criteria were enrolled to determine the frequency of GDM in females presenting in a tertiary care hospital and to compare total cholesterol level in females presented with or without gestational diabetes at term. Age distribution of the patients was done showing 37.19%(n=119) were between 18-25 years of age and 62.81%(n=201) were between 26-35 years of age, mean+sd was calculated as 26.61+4.06 years. Gestational age was calculated as 72.5%(n=232) were between 37-38 weeks of gestation and 27.5%(n=88) had 39 weeks of gestation, mean+sd was calculated as 37.90+0.80 weeks. Body mass index of the patients was calculated as 40%(n=128) between 18.5-24.9, 45.94%(n=147) had 25.0-29.9 while 14.06%(n=45) had >30, mean+sd was calculated as 26.12+3.82. Frequency of gestational diabetes was calculated as 6.88%(n=22) while 93.12%(n=298) had no findings of the morbidity. Comparison of total cholesterol in GDM versus non-GDM shows that 183.95+5.73 mg/dl in GDM group while 165.90+8.91mg/dl was recorded in non-GDM group, p value was calculated as 0.0001 showing a significant difference.

Conclusion: The study concluded that the frequency of GDM in females presenting in a tertiary care hospital is slightly higher than developed countries while on comparison of total cholesterol level, gestational diabetic females were having significantly higher total cholesterol than the females without it.

Published
2018-11-01
How to Cite
1.
SALMAN JAVED ZKAK. Gestational Diabetes Mellitus and Correlation with Serum Total Cholesterol Levels. J Fatima Jinnah Med Univ [Internet]. 1Nov.2018 [cited 20Apr.2024];11(1). Available from: https://ojs.jfjmu.com/index.php/ojs/article/view/29